Locdown GNOME

yum install gconf-editor
App -> System Tool -> Gconf Editor

yum install pessulus
System -> COnfig -> Lockdown editor

yum install sabayon
System -> Admin -> Profile Editor

Reference:

Chapter 4. Locking Down the Desktop: Disabling GNOME Desktop Features
http://www.redhat.com/docs/manuals/enterprise/RHEL-4-Manual/desktop-guide/ch-ddg-lockdown.html
http://www.linuxtopia.org/online_books/centos_linux_guides/centos_desktop_deployment_guide/ch-ddg-lockdown.html

Introduction to Disabling GNOME Desktop Features
http://library.gnome.org/admin/system-admin-guide/2.22/lockdown-1.html.en
http://library.gnome.org/admin/system-admin-guide/2.22/gconf-0.html.en

Desktop Administrators' Guide to GNOME Lockdown and Preconfiguration
http://sayamindu.randomink.org/soc/deployment_guide/deployment_guide.html

Disable Gnome Right-click?
http://ubuntuforums.org/showthread.php?t=515689

KDE
Kiosktool locks down KDE users' desktops
http://www.linux.com/feature/114306
http://extragear.kde.org/apps/kiosktool/